For high-risk groups

What is high risk for bipolar disorder?

People deemed at high risk for bipolar disorder can be identified by having a family history of the disorder and/or having subclinical symptoms of depression and/or mania that are not severe enough for a diagnosis. Reducing the development of severe symptoms may increase the probability of good long-term outcomes.

The course of bipolar disorder and its treatment response tends to worsen over time, highlighting the importance of early intervention. Over the last 15 years, a biopsychosocial framework for bipolar disorder has obtained growing recognition and an increasingly multimodal treatment approach has emerged. Accordingly, along with psychopharmacological treatments, psychosocial therapies have been proposed as a means of addressing psychological vulnerabilities, family distress, and life stress.

What is the evidence for psychosocial treatments for people at high risk for bipolar disorder?

Moderate to low quality evidence suggests there are benefits of early interventions, particularly family-orientated therapies, for improving mood and functioning in children and adolescents at risk of bipolar disorder. There were no reviews that focussed on adults at risk.

April 2019

Last updated at: 5:29 am, 15th May 2019
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Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.