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How are amphetamines relevant to treatment of schizophrenia? 

Amphetamines are potent stimulants that are used to treat attention deficit hyperactivity disorder, narcolepsy, and obesity. Amphetamines may also be related to an increased risk, or worsening, of psychoic symptoms. Amphetamines are not suggested as an adjuctive treatment, but rather as an investigation into their effects on symptoms.

What is the evidence on amphetamines?

Moderate quality evidence suggests single-dose dexamfetamine or methylphenidate increases severity or frequency of positive symptoms, particularly in patients who are not in remission.


July 2016

Page last updated: 4:29  20 January 2018

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