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What are analeptics? 

A supplementary, or adjunctive, treatment is administered in conjunction with a patient’s ongoing antipsychotic therapy. Analeptics, such as modafinil, have been suggested as potential adjunctive treatments for schizophrenia. Modafinal is a wake-promoting drug (mechanisms of action unknown) which is thought to help with the sedation side-effects of antipsychotics.

What is the evidence on adjunctive analeptics?

Moderate to high quality evidence suggests adjunctive modafinil or armodafinil may improve overall psychopathology with no adverse effects when compared to placebo.


July 2016

Page last updated: 4:30  20 January 2018

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