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Translocator protein

What is translocator protein?

Translocator protein was first recognised as an outer membrane protein that binds benzodiazepine drugs. It is now known to be involved in several complex cellular processes, including cholesterol transport, porphyrin transport, inflammation, and tumor progression. It is also implicated in Parkinson’s and Alzheimer’s disease, and has recently been investigated in people with schizophrenia.

What is the evidence for translocator protein?

Moderate quality evidence finds reduced translocator protein in the frontal cortex, the temporal cortex, and the hippocampus of people with schizophrenia., as measured using positron-emission tomography.

December 2019

Last updated at: 6:46 am, 18th December 2019
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Fact Sheet Technical Commentary

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.