Environmental toxins

How are environmental toxins related to risk for schizophrenia?

Exposure to environmental toxins can cause problems to both physical and mental health. Pollutants of main public health interest involve organic and elemental carbons, metals such as lead, polycyclic aromatic hydrocarbons, carbon monoxide, ozone, nitrogen dioxide, sulphur dioxide, and perchloroethylene commonly used in dry cleaning. Being born or raised in an urban environment has been related to a higher incidence of schizophrenia, and air pollution could be one of the explanatory factors.

What is the evidence for environmental toxins as a risk factor for schizophrenia?

Moderate to low quality evidence suggests exposure to high levels of air pollution may be associated with increased risk for schizophrenia. Prenatal and early childhood exposure to perchloroethylene may also be associated with increased risk of schizophrenia.

March 2019

Last updated at: 4:54 am, 16th March 2019
To view documentation related to this topic download the files below
Fact Sheet Technical Commentary

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.