How is nicotine relevant for schizophrenia? 

The proportion of tobacco smokers amongst people with schizophrenia tends to be much higher than in the general population (for information, see comorbid conditions substance use/smoking topic). This has led to the suggestion that perhaps nicotine (the psychoactive component of tobacco), in addition to ongoing antipsychotic medication, is exerting beneficial effects for symptom severity or every day functioning.

Is there any evidence for the use of nicotine as a treatment for schizophrenia?

No evidence is available to support the use of nicotine for relieving symptoms or improving functioning in people with schizophrenia.

March 2019

Last updated at: 12:02 am, 21st March 2019
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Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.