Topics tagged with "High risk of psychosis"

For high-risk groups

What are high-risk groups? A key target of early intervention is “indicated prevention” for individuals at high risk of psychosis who have been identified with early signs of the disorder, but do not meet any diagnostic criteria. There are two key approaches for identifying people with early signs. The first approach is based on Huber’s Basic Symptoms, which focuses on a detailed way of describing phenomenological (subjective) disturbances in the domains of perception, cognition, language, motor function, will, initiative and level of energy, and stress tolerance. Because the basic symptoms refer only to subtle subjectively experienced abnormalities, they may reflect…

Cognition in high-risk groups

Who are people at high-risk of psychosis? There are two key approaches for identifying people with early signs that may suggest a high risk of developing psychosis or schizophrenia. The first approach is based on Huber’s Basic Symptoms, which focuses on a detailed way of describing phenomenological (subjective) disturbances. Because the basic symptoms refer only to subtle subjectively experienced abnormalities, they may reflect an earlier phase in the disease process than the second approach, which identifies at-risk mental states as a combination of; a family history of psychosis (familial risk) plus non-specific symptoms and recent decline in functioning; recent onset…

Treatments for high-risk groups

What are high-risk groups? The primary aims of early intervention are to prevent or delay future transition to psychosis in high-risk individuals with early symptoms, and to reduce symptom severity in individuals following a first episode of psychosis. A key target of early intervention is “indicated prevention”, for individuals at high risk of psychosis who have been identified with detectable signs of possible disorder, but do not meet any diagnostic criteria for disorder. There are two key approaches for identifying patients with early signs that may suggest an ultra-high risk (UHR) of developing psychosis. The first approach is based on…

Early detection

What is early detection of psychosis? Early detection refers to the correct identification of individuals who are at high risk of developing schizophrenia, with an emphasis on the development of frank psychosis. Several assessment tools have been constructed to effectively identify such individuals. Sensitivity of an assessment tool refers to the proportion of people who develop psychosis that were previously identified by the assessment tool as being at high risk. Specificity is the proportion of people who do not develop psychosis that were previously identified as not being at high risk. Assessment tools therefore aim to have both high sensitivity…

First-episode psychosis

What are outcomes for people with first-episode psychosis or high-risk mental states? After being identified as having high-risk mental states, or after an initial diagnosis of psychosis, relevant outcomes over the years following include transition to psychosis or schizophrenia, symptom severity, recovery and remission, relapse, employment, functioning, relationships, and quality of life. Investigating these outcomes and the factors influencing them provides insight into early treatment strategies. What is the evidence for outcomes in people with first-episode psychosis or high-risk mental states? Moderate quality evidence suggests up to 80% of people have good or intermediate outcomes following a first episode of…

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