Maternal illness – NeuRA Library https://library.neura.edu.au NeuRA Evidence Libraries Tue, 26 Apr 2022 02:29:59 +0000 en-AU hourly 1 https://wordpress.org/?v=5.8 https://library.neura.edu.au/wp-content/uploads/sites/3/2021/10/cropped-Library-Logo_favicon-32x32.jpg Maternal illness – NeuRA Library https://library.neura.edu.au 32 32 Maternal illness during pregnancy https://library.neura.edu.au/bipolar-disorder/risk-factors-bipolar-disorder/non-genetic-risk-factors-bipolar-disorder/maternal-illness-during-pregnancy/ Thu, 04 Apr 2019 03:58:31 +0000 https://library.neura.edu.au/?p=15263 How is maternal illness during pregnancy related to risk for bipolar disorder? Illness during pregnancy, particularly involving infectious agents has been associated with brain and behavioural abnormalities in the offspring, and so have been investigated as possible risk factors for bipolar disorder. What is the evidence for maternal illness during pregnancy as a risk factor for bipolar disorder? Moderate to low quality evidence finds a medium to large increased risk of bipolar disorder after exposure to maternal influenza during pregnancy. However, when the trimesters were analysed separately, the effect remained significant only in the third trimester, and results were found...

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]]> How is maternal illness during pregnancy related to risk for bipolar disorder?

Illness during pregnancy, particularly involving infectious agents has been associated with brain and behavioural abnormalities in the offspring, and so have been investigated as possible risk factors for bipolar disorder.

What is the evidence for maternal illness during pregnancy as a risk factor for bipolar disorder?

Moderate to low quality evidence finds a medium to large increased risk of bipolar disorder after exposure to maternal influenza during pregnancy. However, when the trimesters were analysed separately, the effect remained significant only in the third trimester, and results were found in only one study.

There were no associations between risk of bipolar disorder and urinary tract infections, herpes simplex virus 2, hypertensive problems, or maternal diabetes.

October 2021

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]]> Maternal illness during pregnancy https://library.neura.edu.au/schizophrenia/risk-factors/non-genetic/maternal-illness/ Wed, 15 May 2013 07:14:31 +0000 https://library.neura.edu.au/?p=542 How is maternal illness during pregnancy relevant to people with schizophrenia? Maternal illness during pregnancy with diabetes, toxoplasma gondii, rubella, cytomegalovirus, herpes simplex virus and other microbes have been associated with brain and behavioural abnormalities in the offspring, and so have been investigated as possible risk factors for schizophrenia. Please also see the topic on obstetric complications. What is the evidence for exposure to maternal illness during pregnancy as a risk factor for schizophrenia? Moderate to high quality evidence suggests a small increased risk of psychotic disorders (mostly schizophrenia spectrum or non-affective psychosis) following exposure to herpes simplex type 2...

The post Maternal illness during pregnancy appeared first on NeuRA Library.

]]> How is maternal illness during pregnancy relevant to people with schizophrenia?

Maternal illness during pregnancy with diabetes, toxoplasma gondii, rubella, cytomegalovirus, herpes simplex virus and other microbes have been associated with brain and behavioural abnormalities in the offspring, and so have been investigated as possible risk factors for schizophrenia. Please also see the topic on obstetric complications.

What is the evidence for exposure to maternal illness during pregnancy as a risk factor for schizophrenia?

Moderate to high quality evidence suggests a small increased risk of psychotic disorders (mostly schizophrenia spectrum or non-affective psychosis) following exposure to herpes simplex type 2 in utero. Lower quality evidence suggests exposure to toxoplasma gondii or genitourinary infections in utero may also be associated with increased risk of psychotic disorders. No significant risk was found for herpes simplex type 1, influenza (in any trimester), maternal diabetes, or cytomegalovirus.

High quality evidence suggests a small increased risk of schizophrenia in the offspring of women with increased c-reactive protein levels during pregnancy. Moderate to high quality evidence suggests small effects of increased risk of schizophrenia in the offspring of women with increased cytokines IL-8 or IL-10 during pregnancy.

April 2022

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