Topics tagged with "Schizophrenia and heart problems"

Cardiometabolic changes and weight gain

How are cardiometabolic or weight problems related to schizophrenia? Patient populations that are prescribed antipsychotic agents may experience cardio and metabolic side effects. What are the cardiometabolic side effects? Medicated patients versus population or healthy controls Moderate quality evidence suggests small to medium-sized increased risks of hypertension, low HDL cholesterol, hypertriglyceridemia, diabetes, metabolic syndrome, abdominal obesity and reduced heart rate variability in people with schizophrenia. People with first-episode psychosis and antipsychotic-na├»ve patients also show increased hypertension and reduced heart rate variability, but not other cardiometabolic indices. Medicated patients versus unmedicated patients Moderate to low quality evidence shows that after treatment…

Heart disease

How is heart disease related to schizophrenia? People with schizophrenia may show increased rates of co-occurring conditions, including heart disease. It is unclear if any increased risk is a consequence of the metabolic impact of antipsychotic administration or unhealthy lifestyle choices, or most likely, a combination of both. What is the evidence for comorbid heart disease? Moderate quality evidence finds small increases in rates of coronary heart disease and congestive heart failure in people with schizophrenia, with rates gained from both longitudinal and cross-sectional studies, and from data adjusted for potential confounding factors. Longitudinal studies with adjusted data also show…

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