Topics tagged with "Schizophrenia in the elderly"

Treatments for elderly people and people with late-onset schizophrenia

What is late-onset schizophrenia? Studies of the life course of schizophrenia suggest that positive symptoms tend to reduce with time, while negative symptoms, such as social withdrawal and emotional apathy, increase with time. In contrast, people with late-onset schizophrenia (onset after 40 years of age) and very late-onset schizophrenia (onset after 60 years of age) tend to have predominant positive symptoms and fewer negative symptoms. What is the evidence for treatments for elderly people and people with late-onset schizophrenia? Moderate to low quality evidence suggests no differences in efficacy between risperidone and olanzapine for symptoms of schizophrenia in elderly people…

Late-onset schizophrenia

What is late-onset schizophrenia? Late-onset schizophrenia is defined as onset of psychosis after age 45 years and it has been previously associated with a higher proportion of women, high levels of occupational functioning and marital relationships, as well as more severe paranoid delusions and more visual, tactile, and olfactory hallucinations. It has also been associated with less severe disorganisation and negative symptoms. What is the evidence relating to late-onset schizophrenia? Moderate quality evidence suggests negative life events, history of psychotic symptoms, poor social networks, cognitive impairment, and functional limitations are related to increased rates of late-onset schizophrenia. March 2019

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