Topics tagged with "Schizophrenia treatment adherence"

Mode of administration

What is mode of administration? Studies have shown that about 80% of patients relapse to psychosis within 5 years of initial treatment. This is often due to lack of adherence to antipsychotic medications. Long-acting injectable antipsychotics are a treatment option for patients who are not adhering to treatment or who do not remember to take their oral preparations. What is the evidence for mode of administration? Moderate to high quality evidence shows long-acting injectable second-generation antipsychotics are more effective than placebo injections for symptom improvement. There were small effects of fewer relapses, longer time to relapse, and fewer hospital days…

Treatments for medication non-adherence

What is the importance of┬ámedication adherence? One-quarter to one-half of people with schizophrenia do not adhere to their medication. Non-adherence to maintenance treatments, including antipsychotics, is a widespread issue that plagues clinical management for schizophrenia. It reduces the success of the treatment regimen and the ability to achieve remission from illness, but it also increases the burden for psychotic relapse treatments, emergency admissions and hospitalisation. Greater adherence to treatment can contribute not only to more successful disease management and better quality of life, but also to improved attitudes towards treatment and medication, as well as increasing insight and confidence. In…

Treatment adherence

What is treatment adherence?  Treatment adherence involves taking prescribed treatments (both pharmaceutical and psychosocial) as recommended by the treating physician. What is the evidence for treatment adherence? Moderate quality evidence finds the rate of treatment non-adherence in people with schizophrenia varies between 23% and 49%, with the dropout rate from psychosocial treatments being lower, around 13%. However, moderate to low quality evidence finds no differences in the rates of refusal of treatment or premature termination of treatment between people offered antipsychotics alone and people offered antipsychotics plus psychotherapy. There were also no differences in adherence rates between people of different…

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