Pending enough primary studies, we invite reviews on this topic to be conducted. Alternatively we will endeavour to conduct our own review to fill this gap in the Library.

October 2021

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The post Autonomic nervous system anomalies appeared first on NeuRA Library.

Antecedents, such as behavioural disturbances and psychopathology, are deviations in development that may become evident during childhood or adolescence. The presence of these deviations may foreshadow the later development of bipolar disorder, however most children who exhibit these antecedents do not develop the disorder. Studies exploring antecedents are ideally based on representative, population-based samples that follow the group from birth through childhood and adolescence to adulthood.

What is the evidence from long-term studies for behavioural disturbances and psychopathology as antecedents of bipolar disorder?

Moderate quality evidence suggests an increased risk of bipolar disorder in adulthood with a childhood history of attention problems (including ADHD), aggressive behaviour (but not irritability), internalising or externalising behaviour, social isolation, or peer rejection. There may also be an increased risk of bipolar disorder with prior conduct or oppositional defiant disorder, disruptive or criminal behaviour, impulsivity, or anxiety disorders (e.g. generalised, separation, panic, PTSD).

People with a history of mood swings, subclinical depression or mania, cyclothymic disorder, higher frequency and loading of depression, early onset of depression disorders or episodes, or psychotic symptoms (particularly if accompanied by depression), may also be at an increased risk of developing bipolar disorder.

October 2021

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The post Behaviour and psychopathology appeared first on NeuRA Library.

Antecedents, including cognitive anomalies, are usually subtle deviations in development that may become evident during childhood or adolescence. The presence of these deviations may foreshadow the later development of bipolar disorder, however most children who exhibit deviations do not develop the disorder. Studies exploring antecedents are ideally based on representative, population-based samples that follow the group from birth through childhood and adolescence to adulthood.

What is the evidence from long-term studies on cognitive anomalies as antecedents of bipolar disorder?

Moderate to low quality evidence suggests a medium-sized effect of low IQ in childhood, particularly measured on attention and working memory scales, in people who developed bipolar disorder or mania in adulthood. However, this finding is not consistent across studies, and there is also evidence of a large association between high childhood IQ and mania in adulthood.

October 2021

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The post Cognition appeared first on NeuRA Library.

Pending enough primary studies, we invite reviews on this topic to be conducted. Alternatively, we will endeavour to conduct our own review to fill this gap in the Library.

October 2021

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The post Eye tracking anomalies appeared first on NeuRA Library.

Pending enough primary studies, we invite reviews on this topic to be conducted. Alternatively, we will endeavour to conduct our own review to fill this gap in the Library.

October 2021

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The post Face emotion processing appeared first on NeuRA Library.

Pending enough primary studies, we invite reviews on this topic to be conducted. Alternatively, we will endeavour to conduct our own review to fill this gap in the Library.

October 2021

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The post Height and BMI appeared first on NeuRA Library.

Pending enough primary studies, we invite reviews on this topic to be conducted. Alternatively we will endeavour to conduct our own review to fill this gap in the Library.

October 2021

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The post IQ and academic performance appeared first on NeuRA Library.

Antecedents, including language problems, are usually subtle deviations in development that may become evident during childhood or adolescence. The presence of these deviations may foreshadow the later development of bipolar disorder, however most children who exhibit deviations do not develop the disorder. Studies exploring antecedents are ideally based on representative, population-based samples that follow the group from birth through childhood and adolescence to adulthood.

What is the evidence from long-term studies on language problems as antecedents of bipolar disorder?

Moderate to low quality evidence suggests a medium-sized effect of poor expressive language, but not receptive language, in childhood of people who developed mania in adulthood. There was no association with childhood speech problems in general and later bipolar disorder.

October 2021

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The post Language appeared first on NeuRA Library.

Pending enough primary studies, we invite reviews on this topic to be conducted. Alternatively we will endeavour to conduct our own review to fill this gap in the Library.

October 2021

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The post Minor physical anomalies appeared first on NeuRA Library.

Antecedents, including motor functioning, are usually subtle deviations in development that may become evident during childhood or adolescence. The presence of these deviations may foreshadow the later development of bipolar disorder, however most children who exhibit deviations do not develop the disorder. Studies exploring antecedents are ideally based on representative, population-based samples that follow the group from birth through childhood and adolescence to adulthood.

What is the evidence on motor dysfunction as an antecedent of bipolar disorder?

Moderate to low quality evidence suggests a large effect of poor motor development in the childhood (at ~ 3 years of age) of people who developed mania in adulthood. There may also be more tics and unsteadiness, and more neurological problems in general in the childhood of people who developed affective psychosis in adulthood. Affective psychosis is a broad category that includes bipolar disorder.

October 2021

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The post Motor dysfunction appeared first on NeuRA Library.