Countries are increasingly allowing cannabis derivatives such as cannabinoids (tetrahydrocannabinol [THC] and cannabidiol [CBD]) to be made available for medicinal purposes, including for the treatment of mental disorders. Medicinal cannabis refers to any part of the cannabis plant, such as flowers, buds, leaves, or full plant extracts. Pharmaceutical cannabinoids refer to pharmaceutical-grade medicinal extracts with defined and standardized THC, CBD, or a combination of both and synthetic cannabinoid derivatives. This topic assesses the effectiveness of both medicinal cannabis and pharmaceutical cannabinoids for bipolar disorder.

What is the evidence for medicinal cannabis?

Moderate to low quality evidence finds no improvement in depression symptoms with THC compared to placebo. There was more sedation, anxiety, panic, depersonalization, and psychotic disturbances with THC.

November 2021

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The post Medicinal cannabis appeared first on NeuRA Library.

Countries are increasingly allowing cannabinoids (tetrahydrocannabinol [THC] and cannabidiol [CBD]) to be made available for medicinal purposes, including for the treatment of mental disorders. Medicinal cannabis refers to any part of the cannabis plant, such as flowers, buds, leaves, or full plant extracts. Pharmaceutical cannabinoids refer to pharmaceutical-grade medicinal extracts with defined and standardised THC, CBD, or a combination of both and synthetic cannabinoid derivatives.

What is the evidence regarding cannabinoids for PTSD?

Moderate to low quality evidence finds no consistent improvement in PTSD symptoms with cannabinoids. There may be more adverse events with cannabinoids than with a placebo. Few trials have been conducted to date.

August 2021

Image: ©Ilya- stock.adobe.com

The post Medicinal cannabis appeared first on NeuRA Library.

Countries are increasingly allowing cannabinoids (tetrahydrocannabinol [THC] and cannabidiol [CBD]) to be made available for medicinal purposes, including for the treatment of mental disorders. Medicinal cannabis refers to any part of the cannabis plant, such as flowers, buds, leaves, or full plant extracts. Pharmaceutical cannabinoids refer to pharmaceutical-grade medicinal extracts with defined and standardised THC, CBD, or a combination of both, and synthetic cannabinoid derivatives.

What is the evidence for cannabinoids for schizophrenia?

Moderate to low quality evidence finds no improvement in overall and positive symptoms with adjunctive CBD or THC compared to placebo. Negative and cognitive symptoms may worsen with adjunctive THC.

September 2020

Image: ©Lifeking – stock.adobe.com

The post Medicinal cannabis appeared first on NeuRA Library.