What are cannabinoids?

Countries are increasingly allowing cannabinoids (tetrahydrocannabinol [THC] and cannabidiol [CBD]) to be made available for medicinal purposes, including for the treatment of mental disorders. Medicinal cannabis refers to any part of the cannabis plant, such as flowers, buds, leaves, or full plant extracts. Pharmaceutical cannabinoids refer to pharmaceutical-grade medicinal extracts with defined and standardised THC, CBD, or a combination of both and synthetic cannabinoid derivatives. This topic assesses the effectiveness of both medicinal cannabis and pharmaceutical cannabinoids for PTSD.

What is the evidence on cannabinoids for PTSD?

Moderate to low quality evidence finds no consistent improvement in PTSD symptoms or other outcomes with cannabinoids. There may be more adverse events with cannabinoids than with a placebo.

August 2021

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Last updated at: 3:43 am, 28th July 2021
To view documentation related to this topic download the files below
Fact Sheet Technical Commentary
Tags:  Cannabidiol CBD THC

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.