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Premenstrual syndrome

What is premenstrual syndrome in bipolar disorder?

Premenstrual syndrome involves emotional and behavioural symptoms that occur during the five days before menses for at least three menstrual cycles in a row. At least one affective and one somatic symptom must be present. Affective symptoms include depression, angry outbursts, irritability, anxiety, confusion, and social withdrawal. Somatic symptoms include breast tenderness, abdominal bloating, headache and swelling of extremities.

What is the evidence for premenstrual syndrome?

Moderate quality evidence finds an association between premenstrual syndrome and higher risk of bipolar disorder and mood symptom exacerbation.

October 2021

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Last updated at: 11:36 pm, 25th October 2021
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