Wilson’s disease

What is Wilson’s disease in bipolar disorder?

Wilson’s disease is rare disorder that prevents the body from eliminating copper. It is caused by mutations in a gene that results in an accumulation of the metal in the liver, central nervous system, kidneys and other organs. Wilson’s disease usually presents in childhood, but sometimes in adolescence or young adulthood, and may be accompanied by psychiatric symptoms.

What is the evidence for Wilson’s disease?

Moderate to low quality evidence suggests an increased risk of bipolar disorder, and to a lesser extent, major depression, in people with Wilson’s disease.

October 2021

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Last updated at: 12:33 am, 26th October 2021
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