Familial coaggregation

What is familial coaggregation in bipolar disorder?

Familial coaggregation is the rate of related disorders found in a family. Many studies have suggested a fundamental association between schizophrenia and bipolar disorder. Many family studies have investigated the possibility of this association by assessing whether schizophrenia and bipolar disorder diagnoses may cluster within the same extended family.

What is the evidence for familial coaggregation?

Moderate to low quality evidence suggests high familial coaggregation of schizophrenia and bipolar disorders, with first-degree relatives of people with schizophrenia or bipolar showing an increased risk of developing either disorder.

October 2021

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Last updated at: 1:09 pm, 30th March 2022
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Fact Sheet Technical Commentary
Tags:  Coaggregation

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