Neurotrophins
What are neurotrophins in PTSD?
Neurotrophins, such as brain-derived neurotrophic factor (BDNF) and nerve growth factor, are altered in bipolar disorder and schizophrenia. They regulate neuronal survival and growth during development. Effects of neurotrophins on neuronal transmission in the hippocampus, cortex, cerebellum, and basal forebrain are important for learning and memory processes.
What is the evidence for changes in neurotrophins in people with PTSD?
Moderate to low quality evidence found no significant differences in BDNF levels between people with PTSD and controls without PTSD.
August 2021
Image: ©Giovanni Cancem – stock.adobe.com
Last updated at: 4:27 pm, 9th December 2021
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Fact Sheet Technical Commentary
Fact Sheet Technical Commentary
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Neurotrophins
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Biochemical changes
- Brain pH and lactate
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Incidence and prevalence
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Prevalence
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