What is licarbazepine treatment for bipolar disorder?

Licarbazepine is an anticonvulsant used primarily in the treatment of epilepsy. Anticonvulsant medications influence the actions of neurotransmitters leading to a decrease in brain cell (neuron) excitability.

What is the evidence for licarbazepine as a treatment for bipolar disorder?

Moderate quality evidence suggests licarbazepine is less effective than tamoxefin or risperidone for acute mania symptoms. There may be more discontinuation of treatment with licarbazepine than with olanzapine. There were no significant differences in acute mania symptoms between treatment with licarbazepine and placebo or other medications.

November 2021

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Last updated at: 1:27 pm, 15th February 2022
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