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Vitamin B

How is vitamin B related to bipolar disorders?

Vitamin B12, B6 and folate (vitamin B9) play important roles in the development, maintenance, and function of the brain. Vitamin B is important for critical cellular processes such as the synthesis of nucleic acids for DNA, and the metabolism of amino acids and other vitamins. However, any relationship between vitamin B levels and risk of psychiatric disorders remains unclear.

What is the evidence for vitamin B alterations in people with bipolar disorder?

High quality evidence suggests a small reduction in serum folate levels in people with bipolar disorder compared to people without bipolar disorder. No review was identified that assessed other vitamin B levels.

December 2021

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Last updated at: 5:59 pm, 9th December 2021
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Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.