What is the P200 event-related potential? 

The P200 wave is an event-related brain potential (ERP) measured using electroencephalography (EEG). P200 refers to a spike in activity approximately 150 to 250ms following presentation of a target stimulus that is most commonly auditory, although response is also obtained following somatosensory and visual events. The P200’s latency and amplitude vary with aspects of selective attention or stimulus encoding. Latency is considered a measure of stimulus classification speed, and amplitude is proportional to the amount of attentional resources devoted to the task and the degree of information processing required. Amplitude and latency may be measured using tasks using ‘standard’ and ‘oddball’ stimuli, where the subject is asked to react only to ‘oddball’ target stimuli that are hidden as rare occurrences amongst a series of more common, ‘standard’ stimuli.

What is the evidence on P200 event-related potential?

Moderate quality evidence suggests a small reduction in P200 amplitude and latency at the central midline electrode during standard stimuli conditions, and a small to medium increase in amplitude and latency at the frontal, central and parietal electrodes during oddball stimuli conditions in people with schizophrenia compared to people without schizophrenia.

October 2020

Last updated at: 4:40 am, 29th October 2020
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