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Parkinson’s disease

What is Parkinson’s disease in bipolar disorder?

People with bipolar disorder often have increased rates of co-occurring disorders. The neurotransmitter dopamine may be dysfunctional in both disorders. Moreover, medications used to treat bipolar disorder can induce Parkinson’s symptoms including bradykinesia, resting tremor, rigidity, and postural instability.

What is the evidence for Parkinson’s disease?

Moderate quality evidence suggests a medium-sized increased risk of Parkinson’s disease in people with bipolar disorder compared to people without the disorder. The risk is higher in studies with follow-up periods of less than nine years than in studies with follow-up periods of more than nine years.

October 2021

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Last updated at: 12:45 am, 26th October 2021
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Fact Sheet Technical Commentary
Tags:  Extrapyramidal symptoms

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