Therapies for dual diagnosis
What is dual diagnosis?
Dual diagnosis is a term that refers to having both a mental illness such as bipolar disorder and a substance use problem. Studies of dual diagnosis investigate the effectiveness and availability of treatments for improving outcomes relating to either diagnosis, such as symptoms, functioning, quality of life, substance use, or cognitive problems.
What is the evidence for treatments for dual diagnosis?
Moderate to low quality evidence finds some improvement in symptoms and substance use with cognitive behavioural therapy plus medication. However, these results were not consistently found using different measures of substance use and symptoms.
November 2021
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Last updated at: 11:34 am, 3rd November 2021
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Fact Sheet Technical Commentary
Fact Sheet Technical Commentary
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Dual diagnosis
Substance use
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Antecedents
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Illness course and outcomes
- Absconding
- Age at onset
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- Creativity
- Criminal offending, aggression and violence
- Criminal victimisation
- Cultural differences
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- Drug and alcohol use
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- Psychotic relapse
- Quality of care
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- Sex differences
- Smoking
- Stigma and attitudes towards mental health
- Suicide and self-harm
- Treatment adherence
- Treatment-resistance
- Insights for families
-
Physical features
-
Functional changes
- Body functioning
-
Biochemical changes
- Brain pH and lactate
- cAMP
- Cholesterol
- Dopamine
- Endocannabinoids
- GABA
- Hormonal changes
- Hypothalamic-pituitary-adrenal axis
- Infectious agents
- Inflammation and the immune system
- Lipids
- Neurometabolites
- Neurotrophins
- Nitric oxide
- NMDA receptor function
- Oxidative stress
- S100 Proteins
- Serotonin
- Synaptic proteins
- Trace elements
- Vascular endothelial growth factor
- Vitamin B
- Vitamin D
- Cerebral blood flow and metabolism
- Electrophysiology
- Structural changes
- Brain regions
-
Functional changes
-
Co-occurring conditions
- Mental disorders
-
Physical disorders
- Auditory system dysfunction
- Autoimmune diseases
- Blood disorders
- Cancer
- Cerebrovascular disease
- Dementia
- Dental disease
- Diabetes
- Digestive disorders
- Epilepsy
- Heart disease
- Infectious diseases
- Metabolic syndrome
- Musculoskeletal and connective tissues
- Obesity
- Optical alterations
- Peripheral vascular disease
- Polycistic ovary syndrome
- Postoperative complications
- Reproductive and urological disorders
- Respiratory system dysfunction
- Sexual dysfunction
- Skin disorders
- Sleep apnea
- Thyroid disorders
- Underweight
- Venous thromboembolism
- Substance use
-
Incidence and prevalence
- General
- Incidence
-
Prevalence
- Prevalence in children
- Prevalence in elderly people
- Prevalence in forensic settings
- Prevalence in homeless populations
- Prevalence in indigenous populations
- Prevalence in inpatients
- Prevalence in males vs. females
- Prevalence in migrants
- Prevalence in refugees
- Prevalence in veterans and conflict settings
- Spatial variation in prevalence
- Worldwide prevalence
- General information
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Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.