Optical coherence tomography

What are optical coherence tomography changes in bipolar disorder?

Optical coherence tomography (OCT) is an imaging technology that assesses the thickness of the peripapillary retinal nerve fibre layer, macular thickness, and volume. It has been used to assess neurologic diseases such as multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease, and more recently, in bipolar disorder.

What is the evidence for OCT in people with bipolar disorder?

Moderate to low quality evidence finds a large reduction in overall peripapillary retinal nerve fibre layer thickness in people with bipolar disorder, particularly in the inferior retinal nerve fibre layers.

December 2021

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Last updated at: 5:55 pm, 12th December 2021
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