Medicinal cannabis

What is medicinal cannabis for schizophrenia?

Countries are increasingly allowing cannabinoids (tetrahydrocannabinol [THC] and cannabidiol [CBD]) to be made available for medicinal purposes, including for the treatment of mental disorders. Medicinal cannabis refers to any part of the cannabis plant, such as flowers, buds, leaves, or full plant extracts. Pharmaceutical cannabinoids refer to pharmaceutical-grade medicinal extracts with defined and standardised THC, CBD, or a combination of both, and synthetic cannabinoid derivatives.

What is the evidence for cannabinoids for schizophrenia?

Moderate to low quality evidence finds no improvement in overall and positive symptoms with adjunctive CBD or THC compared to placebo. Negative and cognitive symptoms may worsen with adjunctive THC.

September 2020

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Last updated at: 4:30 am, 15th October 2021
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