What are cannabinoids?

Countries are increasingly allowing cannabinoids (tetrahydrocannabinol [THC] and cannabidiol [CBD]) to be made available for medicinal purposes, including for the treatment of mental disorders. Medicinal cannabis refers to any part of the cannabis plant, such as flowers, buds, leaves, or full plant extracts. Pharmaceutical cannabinoids refer to pharmaceutical-grade medicinal extracts with defined and standardised THC, CBD, or a combination of both, and synthetic cannabinoid derivatives.

What is the evidence for cannabinoids as treatments for schizophrenia?

Moderate to low quality evidence finds no improvement in overall and positive symptoms with adjunctive CBD or THC compared to placebo. Negative and cognitive symptoms may worsen with adjunctive THC.

September 2020

Last updated at: 3:45 am, 29th September 2020
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