What are anticonvulsants? 

Anticonvulsant medications influence the actions of neurotransmitters including glutamate and GABA, leading to a decrease in brain cell (neuron) excitability. Anticonvulsants may be implemented as an immediate therapy for acute symptoms of psychosis, but they may also be used as part of an ongoing treatment regime. Anticonvulsant medication assessed in this topic primarily includes carbamazepine.

What is the evidence for anticonvulsants?

Moderate to low quality evidence suggests carbamazepine may reduce the need for additional anticholinergic drugs to treat side effects compared to antipsychotics. Low quality evidence is unclear of the effects of anticonvulsants for study attrition, relapse, mental state, or adverse effects when compared to antipsychotics.

March 2019

Last updated at: 12:34 am, 21st March 2019
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Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.