What is gabapentin?

Gabapentin is an anticonvulsant used primarily in the treatment of seizure disorders such as epilepsy. Anticonvulsant medications influence the actions of neurotransmitters leading to a decrease in brain cell (neuron) excitability.

What is the evidence for gabapentin as a treatment for bipolar disorder?

Moderate to low quality evidence suggests no differences between gabapentin and placebo for the treatment of mania symptoms.

Low quality evidence is unable to determine differences between groups for treatment discontinuation; an indication of tolerability.

July 2020

Last updated at: 4:25 am, 7th July 2020
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Title Colour Legend:
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Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.