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Treatments for smoking cessation

How is smoking related to schizophrenia?

Tobacco smoking is very common among people with schizophrenia, who often show particularly heavy usage. This poses considerable health risks, may interfere with antipsychotic medications and may place a financial burden on the individual. Heavy cigarette use may contribute to the increased mortality and reduced life expectancy reported within the schizophrenia population.

What is the evidence for interventions for smoking?

Moderate quality evidence finds a medium-sized effect of more smoking cessation with bupropion than with placebo, which was maintained at six months follow-up.

Moderate quality evidence finds varenicline can reduce the number of cigarettes smoked per day and results in more abstaining smoking behaviour, although total cessation rates were no different to placebo.

August 2019

Last updated at: 4:16 am, 21st September 2020
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Fact Sheet Technical Commentary

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.