What are neuropeptides?

Neuropeptides are a class of signaling molecules. They are protein-like molecules that are used by neurons to communicate with each other. Different neuropeptides are involved in different brain functions such as reward, food intake, metabolism, reproduction, social behaviours, and learning.

What is the evidence for neuropeptides in people with PTSD?

Moderate quality evidence found a large effect of lower neuropeptide Y levels in people with PTSD compared to controls without PTSD. This effect was also found in non-medicated samples.

High quality evidence found no significant differences in oxytocin levels between people with PTSD and controls.

August 2021

Image: ©Luka Čulig –

Last updated at: 2:40 am, 2nd August 2021
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Fact Sheet Technical Commentary

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
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