Digestive disorders

How are digestive disorders related to schizophrenia? 

People with schizophrenia may show increased rates of co-occurring conditions, including appendicitis, gastric ulcers, irritable bowel syndrome, or celiac disease.

What is the evidence for comorbid digestive disorders?

Moderate to high quality evidence finds small increases in rates of anemia and celiac disease in people with schizophrenia or other psychotic disorders compared to people without a psychotic disorder. There were also increased rates of schizophenia in people with celiac disease compared to people without celiac disease. There were no increases in rates of Crohn’s disease or ulcerative colitis.

Moderate to low quality evidence suggests people with schizophrenia show an increased risk of mortality from digestive disease.

May 2019

Last updated at: 1:15 am, 7th May 2019
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Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.