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Parkinson’s disease

How is Parkinson’s disease related to bipolar disorder?

People with bipolar disorder often have increased rates of co-occurring disorders. The neurotransmitter dopamine may be dysfunctional in both bipolar disorder and Parkinson’s disease. Moreover, medications used to treat bipolar disorder can induce Parkinson’s symptoms including bradykinesia, resting tremor, rigidity, and postural instability.

What is the evidence for Parkinson’s disease in people with bipolar disorder?

Moderate quality evidence suggests a medium-sized increased risk of Parkinson’s disease in people with bipolar disorder compared to people without bipolar disorder. The risk is higher in studies with follow-up periods of less than nine years than in studies with follow-up periods of more than nine years.

May 2020

Last updated at: 2:24 am, 26th May 2020
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Fact Sheet Technical Commentary

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Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.