Treatments for elderly people and people with late-onset schizophrenia

What is late-onset schizophrenia?

Studies of the life course of schizophrenia suggest that positive symptoms tend to reduce with time, while negative symptoms, such as social withdrawal and emotional apathy, increase with time. In contrast, people with late-onset schizophrenia (onset after 40 years of age) and very late-onset schizophrenia (onset after 60 years of age) tend to have predominant positive symptoms and fewer negative symptoms.

What is the evidence for treatments for elderly people and people with late-onset schizophrenia?

Moderate to low quality evidence suggests no differences in efficacy between risperidone and olanzapine for symptoms of schizophrenia in elderly people with schizophrenia. Low quality evidence is unable to determine any differences between other antipsychotic medications for late-onset schizophrenia.

March 2019

Last updated at: 3:37 am, 1st April 2019
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