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How is mortality related to people with bipolar disorder?

The life expectancy of people with a mental illness may be reduced compared to the general population. The reasons are largely unclear, but may in part be related to lifestyle factors such as weight gain, smoking, unhealthy diet and low physical activity. Bipolar disorder may also be associated with increased suicide rates when compared to the general population. This topic assesses the current evidence describing mortality rates in people with bipolar disorder.

What is the evidence regarding mortality rates?

Moderate to high quality evidence suggests a medium-sized effect of increased risk of all-cause mortality in people with bipolar disorder compared to the general population.

There were large effects of increased risk of suicide or other violent deaths, medium-sized effects of increased risk of death from respiratory disease or infections, and small effects of increased risk of death from cardiovascular disease, circulatory disease or cancer.

May 2020

Last updated at: 11:56 pm, 27th May 2020
To view documentation related to this topic download the files below
Fact Sheet Technical Commentary

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.