Topriamate

What is topriamate?

Topriamate is an anticonvulsant medication primarily used to treat epilepsy and migrane headaches. It has also been tested for people with bipolar disorder.

What is the evidence for topriamate for bipolar disorder?

Moderate quality evidence showed no significant differences in mania or mixed symptoms following treatment with topiramate or placebo for up to 12 weeks. There was greater improvement in mania and mixed symptoms with lithium than with topiramate. There were no differences in side effects between topiramate and placebo or lithium.

April 2019

Last updated at: 6:15 am, 2nd April 2019
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Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.