What is topriamate treatment for bipolar disorder?

Topriamate is an anticonvulsant medication primarily used to treat epilepsy and migrane headaches. It has also been tested for people with bipolar disorder.

What is the evidence for topriamate for bipolar disorder?

Moderate quality evidence showed no significant differences in mania or mixed symptoms following treatment with topiramate or placebo for up to 12 weeks. There was greater improvement in mania and mixed symptoms with lithium than with topiramate. There were no differences in side effects between topiramate and placebo or lithium.

November 2021

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Last updated at: 1:26 pm, 15th February 2022
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