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Vascular endothelial growth factor

What is vascular endothelial growth factor?

Vascular endothelial growth factor is a signal protein that stimulates blood vessel development and repair. Overexpression of can cause vascular disease, diabetes, and some cancers. It also plays a role in neuroprotection and regeneration of central nervous system cells and stimulates axonal outgrowth and neuronal differentiation. It is involved in neuronal regeneration after brain injury and in the forming of new neurons in the adult brain.

What is the evidence for vascular endothelial growth factor levels in people with schizophrenia?

Moderate to high quality evidence found higher levels of vascular endothelial growth factor in medicated, multiple-episode patients but not in first-episode patients or in those who were antipsychotic-naive.

October 2020

Last updated at: 2:42 am, 29th October 2020
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Fact Sheet Technical Commentary

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.