Late-onset schizophrenia

What is late-onset schizophrenia?

Late-onset schizophrenia is defined as onset of psychosis after age 45 years and it has been previously associated with a higher proportion of women, high levels of occupational functioning and marital relationships, as well as more severe paranoid delusions and more visual, tactile, and olfactory hallucinations. It has also been associated with less severe disorganisation and negative symptoms.

What is the evidence relating to late-onset schizophrenia?

Moderate quality evidence suggests negative life events, history of psychotic symptoms, poor social networks, cognitive impairment, and functional limitations are related to increased rates of late-onset schizophrenia.

March 2019

Last updated at: 2:54 am, 23rd March 2019
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