Arcuate fasciculus

What is the arculate fasciculus?

The arcuate fasciculus is a bundle of axons that connects the temporal cortex and inferior parietal cortex to locations in the frontal lobe. One of the key roles of the arcuate fasciculus is connecting Broca’s and Wernicke’s areas, which are involved in producing and understanding language. Therefore, there may be anomalies in the arculate fasciculus of people with schizophrenia who experience auditory-verbal hallucinations.

What is the evidence for changes in the arculate fasciculus?

Moderate quality evidence suggests decreased fractional anisotropy in the left, but not the right arcuate fasciculus in people with schizophrenia who experience auditory-verbal hallucinations compared to controls.

March 2019

Last updated at: 2:52 am, 28th March 2019
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