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Arcuate fasciculus

What is the arculate fasciculus?

The arcuate fasciculus is a bundle of axons that connects the temporal cortex and inferior parietal cortex to locations in the frontal lobe. One of the key roles of the arcuate fasciculus is connecting Broca’s and Wernicke’s areas, which are involved in producing and understanding language. Therefore, there may be anomalies in the arculate fasciculus of people with schizophrenia who experience auditory-verbal hallucinations.

What is the evidence for changes in the arculate fasciculus?

Moderate quality evidence found reduced white matter integrity in the bilateral arcuate fasciculus, including bilateral anterior and posterior segments, and the left long segment.

There was reduced white matter integrity in the left, but not the right arcuate fasciculus in people with schizophrenia who experience auditory-verbal hallucinations.

January 2020

Last updated at: 2:36 am, 16th January 2020
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Fact Sheet Technical Commentary

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.