Skin disorders

How are skin disorders related to schizophrenia?

People with schizophrenia often show increased rates of co-occurring conditions, including skin disorders. Psoriasis is a long-term autoimmune condition that accelerates the life cycle of skin cells. This allows cells to build up on the surface of the skin, which form scales and red patches that are often itchy and painful. Pemphigoid is a rare autoimmune disorder that can develop at any age, but is most often seen in elderly patients. It results in skin rashes and blistering on the legs, arms, and abdomen. Alopecia areata is another autoimmune disease, but rather than affecting the skin directly, it is characterised by non-scarring hair loss on the scalp, face or body.

What is the evidence for skin disorders in people with schizophrenia?

Moderate quality evidence finds small increases in rates of psoriasis and pemphigoid in people with schizophrenia or other psychotic disorders, with no differences in rates of alopecia areata.

June 2020

Last updated at: 2:44 am, 19th June 2020
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