Familial coaggregation with bipolar disorder

What is familial coaggregation? 

Familial coaggregation is the rate of related disorders found in a family. Many studies have suggested a fundamental association between schizophrenia and bipolar disorder. Many family studies have investigated the possibility of this association by assessing whether schizophrenia and bipolar disorder diagnoses may cluster within the same extended family.

What is the evidence for familial coaggregation of schizophrenia and bipolar disorder?

Moderate to low quality evidence suggests high familial coaggregation of schizophrenia and bipolar disorder, with first-degree relatives of patients with schizophrenia or bipolar showing an increased risk of developing either disorder.

February 2019

Last updated at: 5:27 am, 26th March 2019
To view documentation related to this topic download the files below
Fact Sheet Technical Commentary

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.