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Optical alterations

How are optical alterations related to bipolar disorder?

People with bipolar disorder may show increased rates of co-occurring conditions. These can include short-sightedness (impaired long distance signt) and long-sightedness (impaired near distance sight), as well as reductions in the peripapillary retinal nerve fibre layer, and in macular thickness and volume.

What is the evidence for optical alterations in people with bipolar disorder?

Moderate to low quality evidence finds a large reduction in overall peripapillary retinal nerve fibre layer thickness in people with bipolar disorder, particularly in the inferior retinal nerve fibre layers.

February 2021

Last updated at: 4:52 am, 1st February 2021
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Fact Sheet Technical Commentary

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.