What is fibromyalgia in bipolar disorder?

Fibromyalgia is a centralised pain syndrome characterised by the presence of chronic widespread pain in association with fatigue, sleep disturbances and cognitive dysfunction. Fibromyalgia has been associated with higher rates of mood recurrences and greater disability. The use of antidepressants in fibromyalgia management may promote manic switches and episodes with mixed features.

What is the evidence for comorbid fibromyalgia?

Moderate quality evidence suggests the overall prevalence of bipolar disorder in people with fibromyalgia is ~15%, which represents a large increased risk when compared to people without fibromyalgia.

October 2021

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Last updated at: 11:12 pm, 25th October 2021
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Fact Sheet Technical Commentary
Tags:  Chronic pain

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