Motor dysfunction

What are antecedents?

Antecedents such as motor dysfunction are subtle deviations in development that may become evident during childhood or adolescence. The presence of these deviations may foreshadow the later development of schizophrenia, however most children who exhibit these antecedents do not develop the disorder. Studies exploring antecedents are ideally based on representative, population-based samples that follow the group from birth through childhood and adolescence to adulthood. These studies can provide unique insights into the changes in developmental trajectories that may be associated with schizophrenia.

What is the evidence for motor dysfunction in childhood?

High quality evidence finds schizophrenia in adulthood is associated with a medium-sized effect of delay in walking unsupported in infancy, and small effects of delays in standing and sitting unsupported in infancy.

High quality evidence suggests youth ≤ 16 years who developed schizophrenia in adulthood were more likely to display deficits in motor function than youth who did not develop the disorder (medium-sized effect).

March 2019

Last updated at: 2:28 am, 23rd March 2019
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Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.