Whole brain volume

What is the whole brain volume? 

Investigation of whole brain volume considers the collective volume of the entire brain in structural imaging, without considering regionally specific differences in the volume of any individual structures. Alternatively, whole brain imaging can also consider overall grey matter or white matter volume.

What is the evidence for whole brain volume changes?

Moderate to high quality evidence suggests people with schizophrenia have reduced whole brain, hemispheric, and grey and white matter volume that may reduce over time. Reduced whole brain volume is also found in people with first-episode schizophrenia. First-degree relatives of people with schizophrenia have reduced total grey matter volume compared to people without schizophrenia, with no differences in white matter or whole brain volume.

March 2019

Last updated at: 1:26 am, 29th March 2019
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NeuRA Libraries

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