Heart disease

How is heart disease related to bipolar disorder?

People with bipolar disorder show increased rates of co-occurring conditions. Heart disease is a common co-occurring disorder. It is unclear if the increased risk of heart disease is a consequence of the metabolic impact of medications or unhealthy lifestyle choices, or most likely, a combination of both.

What is the evidence for heart disease in people with bipolar disorder?

Moderate quality evidence suggests small increased risks of cardiovascular disease, congestive heart failure, and death due to cardiovascular disease in people with bipolar disorder compared to people without bipolar disorder. These findings were adjusted for other variables that may have explained the increased risks.

Moderate to low quality evidence also suggests a large effect of reduced heart rate variability in people with bipolar disorder.

High quality evidence finds no increases in rates of myocardial infarction.

April 2020

Last updated at: 2:49 am, 28th April 2020
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Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.