Psychopathology in relatives

How is psychopathology relevant to relatives of people with schizophrenia?

Due to the significant genetic loading of schizophrenia, first-degree relatives may also show signs of psychopathology. This could include schizophrenia, bipolar disorder or other mental disorders.

What is the evidence regarding psychopathology in relatives?

Moderate to high quality evidence finds no significant increases in anxiety disorders in offspring of people with schizophrenia.

Moderate to low quality evidence also finds no significant increases in disruptive behavioural disorders in offspring of people with schizophrenia.

No systematic reviews were identified that assessed psychopathology in other family members.

April 2022

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Last updated at: 4:16 pm, 31st March 2022
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Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.