Our response to COVID-19

We're supporting people to maintain their wellbeing and manage isolation.

Topics tagged with "First-episode psychosis"

For first-episode psychosis

What is first-episode psychosis? People with a first episode of psychosis experience distressing symptoms such as unusual beliefs or abnormal behaviour (positive symptoms) and/or withdrawal or loss of interest in work or school (negative symptoms). Early intervention programs for schizophrenia and psychosis often combine many elements comprising both pharmaceutical and psychosocial therapies, and may involve enriched therapies that are tailored to an individual’s needs. The conclusions presented here are based on group data, and as such individual treatment programs need to be tailored by trained clinicians. Individual response to treatment can vary in terms of both symptoms and adverse effects….

Treatments for first-episode psychosis

What are the treatments for first-episode psychosis? People with a first episode of psychosis experience distressing symptoms such as unusual beliefs or abnormal behaviour (positive symptoms) and/or withdrawal or loss of interest in work or school (negative symptoms). Early intervention programs for schizophrenia and psychosis often combine many elements comprising both pharmaceutical and psychosocial therapies, and may involve enriched therapies that are tailored to an individual’s needs. The conclusions presented here are based on group data, and as such individual treatment programs need to be tailored by trained clinicians. Individual response to treatment can vary in terms of both symptoms…

Schizophreniform disorder

What is schizophreniform disorder? Schizophreniform disorder is a part of the schizophrenia spectrum of disorders and has sometimes been used as a provisional diagnosis while waiting to see if symptoms improve by six months or progress, resulting in a diagnosis of schizophrenia. DSM-5 requires at least one of the following symptoms is present for a significant portion of the time during a one-month period, but for less than six months: delusions, hallucinations or disorganised speech. Disorganised behaviour (e.g. catatonia) or negative symptoms (e.g. social withdrawal) may also be present. There can be no manic, depressive or mixed manic-depressive episodes, and…

Early detection

What is early detection of psychosis? Early detection refers to the correct identification of individuals who are at high risk of developing schizophrenia, with an emphasis on the development of frank psychosis. Several assessment tools have been constructed to effectively identify such individuals. Sensitivity of an assessment tool refers to the proportion of people who develop psychosis that were previously identified by the assessment tool as being at high risk. Specificity is the proportion of people who do not develop psychosis that were previously identified as not being at high risk. Assessment tools therefore aim to have both high sensitivity…

Pathways to care

What are pathways to care?  The help-seeking efforts made by an individual and their families when symptoms of psychosis are apparent, and the clinical services made available as a result of these efforts, are collectively known as ‘pathways to care’. Pathways to care can also encompass service structures that have not been actively sought by the individual. Understanding pathways to care may improve early intervention strategies and contribute to reducing the duration of untreated psychosis. What is the evidence for pathways to care? Moderate to low quality evidence suggest young people have around three contracts before receiving specific services for…

First-episode psychosis

What are outcomes for people with first-episode psychosis or high-risk mental states? After being identified as having high-risk mental states, or after an initial diagnosis of psychosis, relevant outcomes over the years following include transition to psychosis or schizophrenia, symptom severity, recovery and remission, relapse, employment, functioning, relationships, and quality of life. Investigating these outcomes and the factors influencing them provides insight into early treatment strategies. What is the evidence for outcomes in people with first-episode psychosis or high-risk mental states? Moderate quality evidence suggests up to 80% of people have good or intermediate outcomes following a first episode of…

Duration of untreated psychosis and outcomes

What is duration of untreated psychosis (DUP)? DUP is generally determined as the time from the onset of psychotic symptoms to the initiation of treatment or first clinical presentation, when a diagnosis of first-episode psychosis may be given. Longer DUP has been associated with poorer prognosis and is thought to be a predictor of the likelihood and extent of recovery. As such, understanding the effects of DUP is particularly important because it is potentially modifiable. What is the evidence for DUP and outcomes? Moderate to high quality evidence indicates longer DUP, particularly over 9 months, is associated with more severe…

Duration of untreated psychosis

What is the duration of untreated psychosis (DUP)? DUP is generally determined as the time from the onset of psychotic symptoms to the initiation of treatment or first clinical presentation, when a diagnosis of first-episode psychosis may be given. Longer DUP has been associated with poorer prognosis (see the DUP and outcomes topic). As such, understanding the effects of DUP is particularly important because it is potentially modifiable. What is the evidence for DUP? Moderate to high quality evidence indicates the presence of an obligatory dangerousness criterion for compulsory treatment of mental illness is associated with longer DUP. Moderate quality…

NeuRA Libraries

Title Colour Legend:
Green - Topic summary is available.
Orange - Topic summary is being compiled.
Red - Topic summary has no current systematic review available.