Topics tagged with "Melatonin"


What is melatonin for bipolar disorder? Melatonin is a hormone primarily synthesised by the pineal gland. Secretion of melatonin by the pineal gland shows a circadian rhythm synchronised to the light-dark cycle. Melatonin has been reported to be involved in various important biological functions in the body: sleep regulation, circadian rhythm, immune modulation, reproduction, anti-inflammation, antioxidant, and energy metabolism. Various studies have reported the beneficial effects of melatonin for improving metabolic problems; problems often observed in people taking antipsychotic medications. This topic assesses the potential benefits of adjunctive melatonin for reducing metabolic side effects among people with bipolar disorder who…

Hormonal changes

What are hormones and how do they relate to schizophrenia? Hormones are chemical messengers secreted by the endocrine glands. Hormones travel through the bloodstream to tissues and organs, and control most of the body’s major systems including heart rate, metabolism, mood, sexual function, and growth and development. Neuroactive steroids, including testosterone, dehydroepiandrosterone and its sulphide ester, are important for brain development as they influence synaptic connectivity and neuronal differentiation. Thyroid hormones also play a role in neurodevelopmental processes, such as differentiation of neural cells, synaptogenesis, and myelination. Prolactin is involved in many biological functions including reproduction, pregnancy and lactation, and…

NeuRA Libraries

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