What are neuropeptides?

Neuropeptides are a class of signaling molecules. They are protein-like molecules that are used by neurons to communicate with each other. Different neuropeptides are involved in different brain functions such as reward, food intake, metabolism, reproduction, social behaviours, and learning. For example, the neuropeptides oxytocin and vasopressin have specific effects on social behaviours.

What is the evidence for neuropeptides in people with schizophrenia?

Moderate quality evidence finds a medium-sized reduction in vasopressin in plasma or serum of patients compared to controls, with no differences in vasopressin when measured in cereobrospinal fluid, and no differences in oxytocin measured in blood or cereobrospinal fluid.

October 2020

Last updated at: 3:32 am, 27th October 2020
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